Aloulou Annunziato Bacher Barata Barone Baumjohann Becher Beilhack Berberich-Siebelt Berod Bohle Bopp Borghans Brenner Buchholz Cumano Daniel De Sousa Delacher Diaz-Munoz Eberl Edinger Ellmeier Elo Fazilleau Gerlach Graca Gratz Heissmeyer Ho Hoffmann Hofmann Hogan Huber Huehn Huppa Iannacone Jeker Joller Kekäläinen Klein Krueger Lahesmaa Linterman Liston Martins McNamee Meerwijk Meyer-Hermann Mittrücker Müller Pace Perucha Peterson Piaggio Prinz Richard Roychoudhuri Rudin Salomon Samson Schlenner Schober Schumann Schurich Silva-Santos Soares Sparwasser Stein Stepanek Strid Vaeth Van Wijk Veldhoen Walker Wekerle Whithers Wolkers Zielinski

Ondrej Stepanek

Junior Group Leader

Email:

ondrej.stepanek@img.cas.cz

Group of Adaptive Immunity
Institute of Molecular Genetics of the Czech Academy of Sciences

Videnska 1083
Prague 4, 14220
Czech Republic

Lab Website:

adaptiveimmunity.img.cas.cz/

Research Interests:

We elucidate how T cells make the proper fate decisions to elicit a potent immune protection and maintain self-tolerance at the same time. Our current research projects focus on the mechanisms of T-cell signaling via antigenic and germ-line encoded receptors, discovery and characterization of particular T-cell subsets, and mechanisms of signaling induced by cytokines and co-stimulation receptors. Moreover, we study the biology of a protein complex called BBSome in immune cells and ciliated cells, to understand a rare disease called Bardet-Biedl Syndrome.