Department of Immunology
25 rue du Dr Roux
75724 Paris, France
Our long-term research interest is to understand how the microbiota integrates the immune system and physiology of its mammalian host. With our studies, we aim to provide new tools to regulate inflammatory pathologies and maintain homeostasis and health. In ongoing studies, we address the following research topics:
- The role of the intestinal microbiota in the regulation of pro- and anti-inflammatory T cells
- The regulation of T cells by innate lymphoid cells (ILC)
- The role of the autonomous nervous system in the regulation of T cell and ILC activity.
The experimental strategies to address our research interests include multi-color flow-cytometry, a variety of immunological tools, manipulation of the microbiota, germfree and gnotobiotic mice, optogenetic manipulation of neurons, next generation sequencing and mouse molecular genetics tools.