Department of Immunology
Institut Pasteur
25 rue du Dr Roux
75724 Paris, France
Lab Website:
Research Interests:
Our long-term research interest is to understand how the microbiota imprints and regulates the reactivity of the immune system, and how the nervous system is involved in these cross-talks. With our studies we aim to generate new concepts in physiology and provide new tools to face chronic inflammation and its many pathological consequences. In ongoing studies, we address the following research topics:
- Impact of the symbiotic microbiota in the development and regulation of the immune system.
- Early life imprinting of the immune system by the symbiotic microbiota (the weaning reaction)
- Cross-regulation of the immune and nervous system in cognitive immunity
The experimental strategies to address our research interests include cellular and molecular immunology, in vivo and in vitro approaches, single cell RNA and ATAC seq, tissue imaging at protein and RNA levels, AAV-mediated neuron tracing and manipulation, behavioral tests.