Francesco Annunziato
Meryem Aloulou
Petra Bacher
João Barata
Francesca Barone
Dirk Baumjohann
Burkhard Becher
Andreas Beilhack
Friederike Berberich-Siebelt
Luciana Berod
Barbara Bohle
Tobias Bopp
Jose Borghans
Dirk Brenner
Veit Buchholz
Ana Cumano
Carolin Daniel
Ana de Sousa
Michael Delacher
Manuel Diaz-Munoz
Gerard Eberl
Matthias Edinger
Wilfried Ellmeier
Laura Elo
Nicolas Fazilleau
Carmen Gerlach
Luis Graca
Iris Gratz
Vigo Heissmeyer
Ping-Chih Ho
Petra Hoffmann
Maike Hofmann
Andrew Hogan
Magdalena Huber
Jochen Huehn
Johannes Huppa
Matteo Iannacone
Lukas Jeker
Nicole Joller
Eliisa Kekäläinen
Ludger Klein
Andreas Krueger
Michelle Linterman
Adrian Liston
Vera Martins
Jost Meerwijk
Eóin N. McNamee
Michael Meyer-Hermann
Hans-Willi Mittrücker
Anne Müller
Luigia Pace
Esperanza Perucha
Pärt Peterson
Eliane Piaggio
Immo Prinz
Arianne Richard
Rahul Roychoudhuri
Anna Rudin
Benoit Salomon
Jannike Samson
Susan Schlenner
Kilian Schober
Katrin Schumann
Anna Schurich
Bruno Silva-Santos
Helena Soares
Tim Sparwasser
Jens Stein
Ondrej Stepanek
Jessica Strid
Femke van Wijk
Martin Vaeth
Marc Veldhoen
Lucy Walker
Thomas Wekerle
Dave Whithers
Monika Wolkers
Christina Zielinski
Molecular Pathology
Institute of Biomedicine and Translational Medicine
University of Tartu
Biomedicum
Ravila 19
Tartu 50411
Estonia
Lab Website:
biomeditsiin.ut.ee/en/content/molecular-pathology-research-group
Research Interests:
We study several aspects of the immune system and how it is regulated. Our research directions are:
- Central immune tolerance and the function of the Autoimmune Regulator (AIRE) gene in the thymus.
- Immunopathology of APECED (or APS1) disease, in which patients develop multiple endocrine autoimmune disorders and chronic mucocutaneous candidiasis.
- The role of autoantibodies to type 1 interferon and other cytokines, and their presence among autoimmune patients and in aged individuals
- Age-related changes in old individuals to understand the molecular and cellular drivers of these processes.
We combine molecular and cellular techniques including multi-color flow-cytometry, use genome-wide transcriptomic and epigenetic analyses, and single-cell technologies to study molecular regulation of immune cells.
