Aloulou
Annunziato
Bacher
Barata
Barone
Baumjohann
Becher
Beilhack
Berberich-Siebelt
Berod
Bohle
Bopp
Borghans
Brenner
Buchholz
Cumano
Daniel
De Sousa
Delacher
Diaz-Munoz
Eberl
Edinger
Ellmeier
Elo
Fazilleau
Gerlach
Graca
Gratz
Heissmeyer
Ho
Hoffmann
Hofmann
Hogan
Huber
Huehn
Huppa
Iannacone
Jeker
Joller
Kekäläinen
Klein
Krueger
Lahesmaa
Linterman
Liston
Martins
McNamee
Meerwijk
Meyer-Hermann
Mittrücker
Müller
Pace
Perucha
Peterson
Piaggio
Prinz
Richard
Roychoudhuri
Rudin
Salomon
Samson
Schlenner
Schober
Schumann
Schurich
Silva-Santos
Soares
Sparwasser
Stein
Stepanek
Strid
Vaeth
Van Wijk
Veldhoen
Walker
Wekerle
Whithers
Wolkers
Zielinski
Molecular Pathology
Institute of Biomedicine and Translational Medicine
University of Tartu
Biomedicum
Ravila 19
Tartu 50411
Estonia
Lab Website:
biomeditsiin.ut.ee/en/content/molecular-pathology-research-group
Research Interests:
We study several aspects of the immune system and how it is regulated. Our research directions are:
- Central immune tolerance and the function of the Autoimmune Regulator (AIRE) gene in the thymus.
- Immunopathology of APECED (or APS1) disease, in which patients develop multiple endocrine autoimmune disorders and chronic mucocutaneous candidiasis.
- The role of autoantibodies to type 1 interferon and other cytokines, and their presence among autoimmune patients and in aged individuals
- Age-related changes in old individuals to understand the molecular and cellular drivers of these processes.
We combine molecular and cellular techniques including multi-color flow-cytometry, use genome-wide transcriptomic and epigenetic analyses, and single-cell technologies to study molecular regulation of immune cells.
