Aloulou
Annunziato
Bacher
Barata
Barone
Baumjohann
Becher
Beilhack
Berberich-Siebelt
Berod
Bohle
Bopp
Borghans
Brenner
Buchholz
Cumano
Daniel
De Sousa
Delacher
Diaz-Munoz
Eberl
Edinger
Ellmeier
Elo
Fazilleau
Gerlach
Graca
Gratz
Heissmeyer
Ho
Hoffmann
Hofmann
Hogan
Huber
Huehn
Huppa
Iannacone
Jeker
Joller
Kekäläinen
Klein
Krueger
Lahesmaa
Linterman
Liston
Martins
McNamee
Meerwijk
Meyer-Hermann
Mittrücker
Müller
Pace
Perucha
Peterson
Piaggio
Prinz
Richard
Roychoudhuri
Rudin
Salomon
Samson
Schlenner
Schober
Schumann
Schurich
Silva-Santos
Soares
Sparwasser
Stein
Stepanek
Strid
Vaeth
Van Wijk
Veldhoen
Walker
Wekerle
Whithers
Wolkers
Zielinski
Research group ‘Molecular and Cellular Immunology’
Institute of Pathology
Josef-Schneider-Str. 2
97218 Würzburg
Germany
Lab Website:
Research Interests:
The research group has a special interest in conventional T cells and regulatory T cells.
Here, one focus lies on the expression pattern and activation as well as signal transduction of the transcription factor family ‘NFAT’, we mainly study in mice.
- The role of individual NFAT family members and their isoforms
- The influence of modifications, especially by sumoylation
- The interplay with other transcription (co-) factors
- The overall loss of NFAT expression in various immune cells
The experimental strategies to address our research interests include multi-color flow-cytometry, molecular approaches, cell culture, next generation sequencing including scRNAseq, CyTOF, virus-free CRISPR/Cas9-mediated deletions, transgenic mice and several preclinical mouse models for autoimmune diseases, organoids