Aloulou Annunziato Bacher Barata Barone Baumjohann Becher Beilhack Berberich-Siebelt Berod Bohle Bopp Borghans Brenner Buchholz Cumano Daniel De Sousa Delacher Diaz-Munoz Eberl Edinger Ellmeier Elo Fazilleau Gerlach Graca Gratz Heissmeyer Ho Hoffmann Hofmann Hogan Huber Huehn Huppa Iannacone Jeker Joller Kekäläinen Klein Krueger Lahesmaa Linterman Liston Martins McNamee Meerwijk Meyer-Hermann Mittrücker Müller Pace Perucha Peterson Piaggio Prinz Richard Roychoudhuri Rudin Salomon Samson Schlenner Schober Schumann Schurich Silva-Santos Soares Sparwasser Stein Stepanek Strid Vaeth Van Wijk Veldhoen Walker Wekerle Whithers Wolkers Zielinski

Matteo Iannacone, MD PhD

Head, Dynamics of Immune Reponses

Email:

iannacone.matteo@hsr.it

Division of Immunology,
San Raffaele Scientific Institute

Via Olgettina 58
20132 Milano
Italy

Lab Website:

www.iannaconelab.com

Research Interests:

Our research program seeks to dissect the complex dynamics of T cell responses to pathogens and tumors. Since it is still beyond the reach of even the most sophisticated in vitro methodology to simulate the complex interplay of physical, cellular, biochemical, and other factors that influence cell behavior in microvessels and interstitial tissues, we make use of intravital microscopy. This technique is complemented by more traditional molecular, cellular and histological approaches, thus characterizing host-virus interactions at the molecular-, single cell- and whole animal-level. In ongoing studies we address the following research topics:

Functional biology of hepatic CD8+ T cells
Regulation of antiviral CD4+ T cell polarization
Spatiotemporal dynamics of CD8+ T cells within liver tumors