Logo Immunology and Cell Therapies Lab

Immunology and Cell Therapies Lab
Department of Clinical and Experimental Medicine,
University of Florence

Viale Pieraccini 6
50139 Florence, Italy

Lab Website:


Research Interests:

Our expertise is mainly devoted to the fields of immune regulation, functional T cell subsets and cytokines, applied to atopy, immunodeficiencies and autoimmunity. Three main topics characterized our work:

  • Human T helper cell subsets characterization: the main achievements have been:
    • the phenotypic and functional characterization of human Th1, Th2 and Th17 cells
    • Th1-, Th2- and Th17-associated molecules
    • signals able to modulate Th1, Th2 and Th17 development
    • role of Th1, Th2 and Th17 cells in human diseases
  • Human T regulatory cells (Treg) characterization: the main achievement has been the functional characterization of human CD4+ and CD8+ CD25+Foxp3+ Treg cells
  • Characterization of immunosuppressive cell subsets infiltrating tumor masses: Treg and mesenchymal stem cells in renal and head-neck squamous cell carcinoma