Aloulou Annunziato Bacher Barata Barone Baumjohann Becher Beilhack Berberich-Siebelt Berod Bohle Bopp Borghans Brenner Buchholz Cumano Daniel De Sousa Delacher Diaz-Munoz Eberl Edinger Ellmeier Elo Fazilleau Gerlach Graca Gratz Heissmeyer Ho Hoffmann Hofmann Hogan Huber Huehn Huppa Iannacone Jeker Joller Kekäläinen Klein Krueger Lahesmaa Linterman Liston Martins McNamee Meerwijk Meyer-Hermann Mittrücker Müller Pace Perucha Peterson Piaggio Prinz Richard Roychoudhuri Rudin Salomon Samson Schlenner Schober Schumann Schurich Silva-Santos Soares Sparwasser Stein Stepanek Strid Vaeth Van Wijk Veldhoen Walker Wekerle Whithers Wolkers Zielinski
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Lucy S.K. Walker, PhD

Professor of Immune Regulation

Lucy Walker

Email:

lucy.walker@ucl.ac.uk

Logo UCL

Institute of Immunity and Transplantation
Division of Infection & Immunity
University College London
Royal Free Campus

London
NW3 2PF
United Kingdom

Lab Website:

www.lucywalkerlab.com/

Research Interests:

Our group seeks to understand how the immune system is normally regulated to prevent the development of autoimmune diseases like type 1 diabetes and rheumatoid arthritis. We are currently addressing the following research topics:

  • The role of the CTLA4 checkpoint in the control of immune homeostasis
  • How CD4 T cells differentiate during the development of autoimmune diseases
  • The pathways controlling regulatory T cell (Treg) homeostasis and function

We use a combination of in vivo models and patient samples to address our research questions. Commonly used techniques in the lab include multi-parameter flow cytometry, confocal microscopy, lentiviral-mediated gene transduction, immune cell transcriptional analysis and in vitro T cell function assays.