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Institute of Immunity and Transplantation
Division of Infection & Immunity
University College London
Royal Free Campus

United Kingdom

Lab Website:


Research Interests:

Our group seeks to understand how the immune system is normally regulated to prevent the development of autoimmune diseases like type 1 diabetes and rheumatoid arthritis. We are currently addressing the following research topics:

  • The role of the CTLA4 checkpoint in the control of immune homeostasis
  • How CD4 T cells differentiate during the development of autoimmune diseases
  • The pathways controlling regulatory T cell (Treg) homeostasis and function

We use a combination of in vivo models and patient samples to address our research questions. Commonly used techniques in the lab include multi-parameter flow cytometry, confocal microscopy, lentiviral-mediated gene transduction, immune cell transcriptional analysis and in vitro T cell function assays.