Francesco Annunziato
Francesca Barone
Dirk Baumjohann
Andreas Beilhack
Barbara Bohle
Tobias Bopp
Ana Cumano
Ana de Sousa
Gerard Eberl
Matthias Edinger
Wilfried Ellmeier
Laura Elo
Nicolas Fazilleau
Luis Graca
Vigo Heissmeyer
Petra Hoffmann
Magdalena Huber
Jochen Huehn
Johannes Huppa
Matteo Iannacone
Lukas Jeker
Nicole Joller
Ludger Klein
Andreas Krueger
Michelle Linterman
Adrian Liston
Vera Martins
Eóin N. McNamee
Michael Meyer-Hermann
Anne Müller
Luigia Pace
Pärt Peterson
Esperanza Perucha
Anna Rudin
Benoit Salomon
Jannike Samson
Kilian Schober
Katrin Schumann
Tim Sparwasser
Ondrej Stepanek
Jessica Strid
Femke van Wijk
Marc Veldhoen
Lucy Walker
Thomas Wekerle
Dave Whithers
Christina Zielinski
Department Experimental Immunology,
Helmholtz Centre for Infection Research
Inhoffenstr. 7
38124 Braunschweig
Germany
Lab Website:
Research Interests:
Our long-term research interest is to identify cellular players and molecular factors controlling CD4+ helper T cell differentiation and function with the final aim to discover novel biomarkers and molecular targets in order to develop therapeutic approaches for the selective modulation of helper T cell responses. Key expertise lies in multi-color flow cytometry, transcriptomic and epigenetic profiling (RNA seq, scRNA seq, Bi seq, ATAC seq), tailored epigenetic modulation of immune cells, as well as murine infection models. Amongst others, we are presently addressing the following research topics:
- Epigenetic fixation of Foxp3 expression in regulatory T cells
- Epigenetic signatures of helper T cell subsets
- Dynamics of regulatory and effector T cells during viral and bacterial infections
- Role of microbiota for the imprinting of tolerogenic properties in stromal cells of gut-draining lymph nodes
