News, Events and Results

September 2017

Supervisor of the year

ENLIGHT-TEN coordinator Jochen Hühn has been awarded "Supervisor of the Year". Once a year the PhD students at the Helmholtz Centre for Infection Research vote the "Supervisor of the year". Congratulations to Jochen Hühn for winning this title for the third time after 2009 and 2014.

August 2017

Science Immunology article on human cTfr cells as indicators of humoral activity

ENLIGHT-TEN PIs Luis Graca, Ana Sousa, Michelle Linterman and colleagues published an interesting paper on human cTfr cells as indicators of humoral activity in Science Immunology. Have a look.

July 2017

Attractive ESR position as ENLIGHT-TEN PhD student available

Attractive ESR position as ENLIGHT-TEN PhD student available.
For details see https://euraxess.ec.europa.eu/jobs/231722

June 2017

ENLIGHT-TEN ESR Marisa co-author of cell report article

Our ESR Marisa Stebegg contributed to a cell report article. Brucklacher-Waldert et al. show how environmental conditions resulting in cellular stress, such as low metabolite levels, specifically enhance Th17 cell differentiation. Under inflammatory conditions, this stress can substitute for TGF-b signaling resulting in de novo Th17 cell differentiation.

June 2017

FameLab talk of our ESR Luis Almeida

Watch the FameLab talk of our ESR Luis Almeida on the immune system and autoimmune diseases. Have a look.

May 2017

Science Immunology article by ENLIGHT-TEN PI Lucy Walker

Great article by ENLIGHT-TEN PI Lucy Walker in Science Immunology "PD-1 and CTLA-4: Two checkpoints, one pathway?" Have a look.

April 2017

youtube video Thomas Faux explaining ChIP-Seq

Youtube video explaining ChIP-Seq

Our ESR Thomas Faux explains the basics of ChIP sequencing, a biochemical/bioinformatic technique to understand interactions between proteins and DNA on an epigenetic level.
➙ General Public

March 2017

Application for ENLIGHT-TEN summer school on bioinformatics welcome

Application is open for the ENLIGHT-TEN summer school "Data resources and bioinformatics tool for immunologists" which is run in collaboration with EMBL-EBI 12 - 16 June. The course will cover bioinformatics resources available to immunologists as well as analysis pipelines for next generation sequencing experiments, like e.g. ChIP-Seq and RNA-Seq. Application is open for all wet-lab immunologist wishing to learn more about bioinformatics tools and resources to improve their research.

March 2017

ESR position as ENLIGHT-TEN PhD student filled

The position for ESR4 at the Medical University Vienna has been filled. We are pleased to welcome Narendra Dhele to our consortium.

February 2017

Attractive ESR position as ENLIGHT-TEN PhD student available

Attractive ESR position as ENLIGHT-TEN PhD student available.
For details see https://euraxess.ec.europa.eu/jobs/170628

December 2016

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2nd ENLIGHT-TEN newsletter published

2nd ENLIGHT-TEN newsletter no. 2 is published. It can be viewed under menue item ➙ General Public.

June 2016

Review article by ENLIGHT-TEN ESR

ENLIGHT-TEN ESR Luís Almeida published a review on Metabolic pathways in T cell activation and lineage differentiation.

May 2016

1st ENLIGHT-TEN summer school

Students meet in Turku to learn more about the immune system

From 6th - 9th of June the ENLIGHT-TEN ESRs (Early Stage Researchers) and external participants meet in Turku to learn more about the immune system. In addition to lectures, the summer school includes a communication workshop, presentations by the ESRs and a debate on a controversial topic. If you are an ENLIGHT-TEN partner you can access the programme and logistics information at our internal website.

Press release, October 2015

Immunologists for the 21st century

Big data analysis for immunologists - Kickoff meeting of the ENLIGHT-TEN programme

The new Marie Curie training network for immunologists called ENLIGHT-TEN (European Network Linking Informatics and Genomics of Helper T cells) commenced on October 9 with a kickoff meeting of 20 experts from seven European countries. The aim of the network is to develop an interdisciplinary training for young researchers in T cell immunology and big data analysis. The ENLIGHT-TEN programme is coordinated by the Helmholtz Center for Infection Research (HZI) in Braunschweig.

The immune system of our body is characterised by highly complex and extremely dynamic processes which are controlled, to a large extent, by the so-called T helper cells acting as the "conductors of the immune system". They play a central role in many disease processes, such as autoimmunity, chronic infections or tumours, and are therefore expedient targets for new therapies. However, the development of such novel therapeutic concepts requires a comprehensive and detailed understanding of the molecular processes that control the development and mode of action of T helper cells.

This knowledge can be obtained only through the application of modern -omics technologies that currently allow scientists to investigate the building blocks of life and vital processes at molecular detail. This type of investigation generates huge amounts of data, though, e.g. in the scope of sequence or proteome analyses. Special expertise in the area of bio-informatics is required to be able to analyse this vast quantity of data – the so-called big data.

"We need to train a new generation of scientists who feel equally at home in the very different worlds of molecular medicine and bioinformatics analysis of high throughput data", says Prof Jochen Hühn, who is the head of the Experimental Immunology department at the HZI and the coordinator of the ENLIGHT-TEN network. "We will use this interdisciplinary training programme to train young immunologists to not only generate large data resources, but to also independently analyse the data in detail. This will enable them to test their working hypotheses through big data analyses and to elucidate the development and function of T helper cells at molecular detail."

The ENLIGHT-TEN network offers 13 Marie-Skłodowska-Curie doctoral scholarships to highly motivated junior researchers. A total of 16 partners from eight European countries contribute to the project by integrating the young scientists into their research groups. The immunologists therefore from the very beginning establish networks and learn to find their way in various countries and surroundings, in universities and in industry.

For further information about the network and the partners in the consortium, please visit the website www.enlight-ten.eu.