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TCC_EUROPE Online Lecture Series

1st Tuesday each month @ 17:00–18:15 (CET) via ZOOM

If you are interested in joining the TCCE Online Lecture Series, please register via:

us02web.zoom.us/meeting/register/tZEqd-yurj8iGtZIgrpiTUPC5BvAK_5G9pN0

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06.10.2020
Marc Veldhoen
Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa
Generating Tissue Resident Memory T cells

David Withers
Institute of Immunology and Immunotherapy, University of Birmingham
Anti-tumour T cell responses: understanding the ins and the outs of it



20.10.2020
Esperanza Perucha
Centre for Inflammation Biology and Cancer Immunology King’s College London
Cholesterol metabolism: a new pathway to inflammation control

Johannes Huppa
Institute of Hygiene and Applied Immunology, Medical University of Vienna
T-cell antigen recognition in mice and men: insights from molecular imaging



03.11.2020
Dirk Baumjohann
University Hospital Bonn
Continued Bcl6 expression prevents the transdifferentiation of established Tfh cells into Th1 cells during acute viral infection

Luis Graca
Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa
The regulation of antibody production by specialized T follicular helper cells



17.11.2020
Gerard Eberl
Institute Pasteur, Paris
Imprinting of the immune system by the weaning reaction

Jochen Huehn
Helmholtz Centre for Infection Research, Braunschweig
How neonatal infections and microbial colonization affect T cell differentiation



01.12.2020
Ondrej Stepanek
Institute of Molecular Genetics, Academy of Sciences of The Czech Republic, Prague
Regulatory T cells limit IL-2 signaling in self-reactive CD8+ T cells to prevent autoimmune pathology

Lukas Jeker
Department of Biomedicine, University of Basel
The non-coding RNA miR-17~92 is a central mediator of T cell activation



15.12.2020
Magdalena Huber
Institute for Medical Microbiology and Hospital Hygiene, University of Marburg
T cell subsets in health and disease

Wilfried Ellmeier
Institute of Immunology, Medical University of Vienna
The control of T cell-mediated immunity by histone deacetylases



19.01.2021
Matteo Iannacone
San Raffaele Scientific Institute, Milan
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

Christina Zielinski
Technical University Munich
Should I stay or should I go - Regulation of human T cell tissue residence



02.02.2021
Nicole Joller
Institute of Experimental Immunology, University of Zurich
Heterologous immunity - how infection history affects inflammatory diseases

Vera Martins
Instituto Gulbenkian de Ciência, Oeiras
Cell competition vs self-renewal in the thymus



16.02.2021
Katrin Schuhmann
Technical University of Munich
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

Kilian Schober
Technical University of Munich
The T cell receptor - evolution of complex immune responses and advanced genetic engineering for therapy



02.03.2021
Janneke Samsom
Laboratory of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus University Medical Center, Rotterdam
Unravelling the role of T-cell immunoglobulin and ITIM domain+ (TIGIT+) expressing CD4+ T cells in intestinal homeostasis

Lucy Walker
Division of Infection and Immunity, Institute of Immunity and Transplantation, University College London
CTLA-4-mediated control of autoimmunity: mechanisms and predictions



16.03.2021
Adrian Liston
Babraham Institute, Cambridge
Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits

Vigo Heissmeyer
Ludwig-Maximilians-University Munich
Cooperative regulation of T cell differentiation by RNA-binding proteins



06.04.2021
Benoit Salomon
Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, Paris
Co-stimulation in Treg biology and function

Femke van Wijk
University Medical Center Utrecht
Human T cell functional dynamics in chronic inflammation



20.04.2021
Luigia Pace
Italian Institute for Genomic Medicine, Candiolo (Turin)
Epigenetic and transcriptional control during CD8+ T cell fate commitment

Michelle Linterman
Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge
A booster dose enhances immunogenicity of the COVID-19 vaccine ChAdOx1 nCoV-19 in aged mice



04.05.2021
Meryem Aloulou
Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), INSERM/CNRS/University of Toulouse
Regulatory T cells program dendritic cells to promote B cell response

Anne Müller
Institute for Molecular Cancer Research, University of Zurich
Treg function during chronic bacterial infection



18.05.2021
Andreas Beilhack
Department of Internal Medicine II, Interdisciplinary Center for Clinical Research Laboratory, University Hospital of Würzburg
Regulation of alloreactive T cells

Laura Elo
Medical Bioinformatics Centre, University of Turku
Computational tools and their application to study T cells



01.06.2021
Eoin McNamee
Department of Biology, Maynooth University, Ireland
Targeting chemokine receptors to reshape T cell – epithelial interaction in the pathogenesis of inflammatory bowel diseases

Ana de Sousa
Instituto de Medicina Molecular João Lobo Antunes, Lisbon
Regulatory T cell development in the human thymus



15.06.2021
Anna Rudin
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy of University of Gothenburg
T cell subtypes in rheumatoid arthritis and the effect of different biological treatments

Ludger Klein
Institute for Immunology, Ludwig-Maximilians-University Munich
Thymus-specific proteases in T cell selection



06.07.2021
Petra Hofman
Regensburg Center for Interventional Immunology, Regensburg
Regulatory T cells in allogeneic bone marrow transplantation

Tobias Bopp
Institute for Immunology, University Medical Center, Johannes Gutenberg-University Mainz
Context-specific regulation of tumor immunity and tolerance by regulatory T cells



19.10.2021
Jens Stein
Department of Oncology, Microbiology and Immunology, University of Fribourg
In vivo analysis of dynamic CD8+ T cell-mediated immune responses

Immo Prinz
Institute of Systems Immunology, University of Hamburg
Innate and adaptive γδ T cells



02.11.2021
Friederike Berberich-Siebelt
Institute of Pathology, University of Würzburg
NFAT and hematopoietic (stem) cell transplantation

Eliane Piaggio
Translational Immunotherapy Team, U932, Institut Curie, Paris
Unraveling Treg biology in human cancer



16.11.2021
Pärt Peterson
University of Tartu
AIRE and anti-interferon antibodies

Michael Delacher
Institute of Immunology, Johannes Gutenberg University Mainz
Tissue-repair T cells



07.12.2021
Leonie Taams
Centre for Inflammation Biology and Cancer Immunology (CIBCI), King’s College London
A joint perspective: T cells in rheumatoid and psoriatic arthritis

Luciana Berod
Institute for Molecular Medicine, Johannes Gutenberg University Mainz
Regulation of T cell responses through fatty acid metabolism



18.01.2022
Maria RODRIGUEZ MARTINEZ
Department Computational Systems Biology, IBM Research Zurich, Switzerland
Artificial intelligence for cancer immunotherapy

Eliisa KEKÄLÄINEN
Department of Bacteriology and Immunology, University of Helsinki, Finland
Immunodeficiency and immune dysregulation caused by a truncating variant of Helios



01.02.2022
Franceso ANNUNZIATO
Department of Experimental and Clinical Medicine, University of Florence, Italy
SARS-CoV-2 and vaccination

Barbara BOHLE
Institute of Pathophysiology and Allergy Research, Medical University of Vienna, Austria
Neutrophils - new players in allergy?



15.02.2022
Dirk BRENNER
Experimental & Molecular Immunology, Department of Infection and Immunity, Luxembourg Institute of Health
cROSsing the line: The metabolic regulation of regulatory T cell function

Dietmar ZEHN
Division of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, Germany
Pyrimidine nucleotide starvation selectively curtails effector but not memory T cell formation



01.03.2022
Tom TAGHON
Department of Diagnostic Sciences, Ghent University, Ghent, Belgium
Molecular drivers of human T cell development

Ping-Chih HO
Department of Fundamental Oncology, University of Lausanne, Switzerland
Mitochondrial dynamics guide T cell anti-tumor immunity



15.03.2022
Joost VAN MEERWIJK
Toulouse Institute for Infectious and Inflammatory Diseases (INSERM/CNRS), University of Toulouse, France
Regulatory T cell development in type I diabetes-prone NOD mice

Carmen GERLACH
Department of Medicine Solna, Division of Rheumatology, Center for Molecular Medicine, Karolinska Institutet, Sweden
CX3CR1 is a graded and universal differentiation marker unifying human and murine T cell differentiation



05.04.2022
Susann SCHLENNER
Adaptive Immunity Laboratory, Department of Microbiology, Immunology and Transplantation, University of Leuven, Belgium
Unstable regulatory T cells

Burkhard BECHER
Institute of Experimental Immunology, University of Zurich, Switzerland
Monocyte education in tissue inflammation



19.04.2022
Tim SPARWASSER
Institut for Medical Microbiology and Hygiene, Johannes Gutenberg-University, Mainz, Germany
Metabolic checkpoints in T cell development and function

Enrico LUGLI
Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Milano, Italy
Molecular control of CD4+ regulatory T cell responses in cancer



03.05.2022
Petter BRODIN
Department of Immunology and Inflammation, Imperial College London, UK
T-cell responses to the microbiota in human newborns

Andrew HOGAN
Human Health Institute, Department of Biology, Maynooth University, Ireland
What fuels MAIT cells in health & disease



17.05.2022
Nicolas FAZILLEAU
Toulouse Institute for Infectious and Inflammatory Diseases (INSERM/CNRS), University of Toulouse, France
T-cell regulation of B-cell responses

José BORGHANS
Leukocyte Dynamics Group, Center for Translational Immunology, University Medical Center Utrecht, The Netherlands
Quantification of T-cell dynamics in health and disease



07.06.2022
Andreas KRUEGER
Institute for Molecular Medicine, Goethe University, Frankfurt, Germany
Molecular and cellular control of intrathymic T-cell development

Bruno SILVA SANTOS
Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
Layers of regulation of effector gamma-delta T cell differentiation



21.06.2022
Arianne RICHARD
Babraham Institute, Cambridge, UK
Transcriptional mechanisms of cytotoxic T lymphocyte activation

Mark ANSEL
Department of Microbiology & Immunology, Sandler Asthma Basic Research Center, University of California San Francisco, USA
RNA regulation of T cell-mediated immunity



05.07.2022
Hannes STOCKINGER
Institute of Applied Immunology, Medical University of Vienna, Austria
Lipid-modifications in early T cell receptor signaling

Henrique VEIGA-FERNANDES
Champalimaud Centre for the Unknown, Lisbon, Portugal
Neuronal regulation of immune fitness



04.10.2022
Anna SCHURICH
Department of Infectious Diseases, School of Immunology and Microbial Sciences, Guy’s Hospital, King’s College London, UK
Therapeutic T cell function, metabolism and exhaustion

Nicole BOUCHERON
Institute of Immunology, Medical University of Vienna, Austria
Rin-like, a gatekeeper of T follicular helper cell differentiation



01.11.2022
Monika WOLKERS
Department of Hematopoeisis, Sanquin, Amsterdam, The Netherlands
Regulation of T cell function by post-transcriptional events

Martin VAETH
Metabolism and Immune Cell Signaling Group, Würzburg Institute of Systems Immunology, Würzburg, Germany
Mitochondrial integrity safeguards the stemness of exhausted T cells



06.12.2022
Petra BACHER
Institute of Immunology & Institute of Clinical Molecular Biology, Christian-Albrecht-University of Kiel, Germany
Regulation of tolerance and inflammation by human antigen-specific T helper cells

João BARATA
Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
Gone wild: IL-7 and IL-7R in T-cell leukemia



10.01.2023
Maike HOFFMANN
Liver Immunology Lab, Department of Medicine II, Medical Center – University of Freiburg, Germany
CD8+ T cell dysfunction in chronic viral infections in humans

Veit BUCHHOLZ
Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Germany
Defining the origin of exhausted CD8 T cell responses to chronic infection and malignancy



07.02.2023
Carolin DANIEL
Institute of Diabetes Research, Group Immune Tolerance Type 1 Diabetes, Helmholtz Diabetes Center at Helmholtz Center Munich, Germany
Regulators of regulatory T cells in Type 1 Diabetes

Thomas KORN
Institute for Experimental Neuroimmunology, Klinikum rechts der Isar, Technical University of Munich, Germany
Shaping of T cell responses in neuromyelitis optica



07.03.2023
Stephanie HUMBLET-BARON
Department of Microbiology, Immunology and Transplantation, Laboratory of Adaptive Immunology, KU Leuven, Leuven, Belgium
Calcium signaling and immunodeficiency

Riitta LAHESMAA
Molecular Systems Immunology Group, Turku Bioscience Centre, Turku, Finland
New regulators of human T cell differentiation



04.04.2023
David SANCHO
Laboratory of Immunobiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
Mitochondrial Oma-1 in the regulation of T cell priming and memory generation

Rahul ROYCHOUDHURI
Department of Pathology, University of Cambridge, UK
Enhancing T cell immunity to cancer metastasis



02.05.2023
Iris GRATZ
Department of Biosciences, University of Salzburg, Austria
Human cutaneous T cells in inflammatory skin disease

Manuel DIAZ-MUNOZ
Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), France
Postranscriptional control of T-cell homeostasis



06.06.2023
TBA
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07.11.2023
Omer DUSHEK
Laboratory for Molecular Immunology, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, UK
T cell antigen sensitivity and discrimination by TCRs and CARs

Johanne JACOBSEN
Laboratory of Immunoregulation and T Cell Biology, University of Oslo, Rikshospitalet, Norway
T cells as regulators of germinal center kinetics



05.12.2023
Stefan FESKE
Department of Pathology, NYU School of Medicine, New York, USA
Beyond Ca2+: Novel ion channels regulating adaptive immunity

Silvia MONTICELLI
Molecular Immunology, Institute for Research in Biomedicine, Bellinzona, Switzerland
Regulatory networks in effector T lymphocytes



06.02.2024
Robert KÖCHL
School of Immunology & Microbial Sciences, King’s College London, UK
Mechanobiological control of cytotoxic T cell-mediated anti-tumour responses

David SANSOM
University College London, UK
Studying molecular interactions in the CTLA-4 and PD-1 checkpoints



05.03.2024
Michele MISHTO
Molecular Immunology Laboratory, The Francis CRICK Institute, UK
CD8+ T cell response against noncanonical epitopes

Christian Schmidl
Leibniz Institute for Immunotherapy, Regensburg, Germany
Dissecting gene-regulation in human tumor-infiltrating lymphocytes



02.04.2024
Riitta LAHESMAA
Molecular Systems Immunology Group, Turku Bioscience Centre, Turku, Finland
New regulators of human T cell differentiation

Lisa VAN BAARSEN
Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, The Netherlands
Fibroblasts steering the lymph node environment



07.05.2024
Susana Minguet
Faculty of Biology, University of Freiburg, Germany
From the basic mechanism of antigen receptor activation to innovative immunotherapies

Shinya Sakaguchi
Shinya Sakaguchi
Role of histone deacetylases for T cell exhaustion



04.06.2024
Alexander Scheffold
Institute of Immunology, University of Kiel, Germany
Autoantigen-specific T cell responses in human autoimmune diseases

Tapio Lonnberg
Turku Bioscience Centre, University of Turku, Finland
Single-cell analysis of tissue homing T cell clones in immune-mediated refractory arthritis



01.10.2024
Megan MacLeod
School of Infection and Immunity, University of Glasgow, UK
Diversity in location and function of lung influenza virus specific CD4+ T cells

Milas Ugur
Max Planck Research Group of Systems Immunology, University Würzburg, Germany
T cell circulation in lymph nodes



05.11.2024
Mateo Villa
Division of Rheumatology and Immunology, Department of Internal Medicine, Medical University of Graz, Austria
Metabolic adaptation of T cells to the tissue microenvironment

Maria Mittelbrunn
Centro de Biologia Molecular Severo Ochoa CSIC-UAM, Madrid, Spain
T cells at the crossroad between inflammation and aging



03.12.2024
Jan Böttcher
Institute of Molecular Immunology and Experimental Oncology, TU Munich, Germany
Cells and mechanisms controlling T cell responses in tumors

Merittxell Genesca Ferrer
Infectious Diseases Department, Vall Hebron Research Institute, Spain
T cell responses in HIV persistance


zwei

07.01.2025
(Next Lecture)
Roger Geiger
Systems Immunology, Institute for Research in Biomedicine, Bellinzona, Switzerland
Systems analyses of anti-tumor T cell responses

Feng Hefeng
Department of Infection and Immunity, Luxembourg Institute of Health, Luxembourg
Immunoageing in T cells and its link to Parkinson’s disease



04.02.2025
Andrew Cope
Centre for Rheumatic Diseases, King’s College London, UK
The immunobiology of rheumatoid arthritis: insights from functional genomic studies

Joris Van Der Veeken
Research Institute of Molecular Pathology, Vienna, Austria
Foxp3-dependent programming of regulatory T cells



04.03.2025
Marga Dominguez Villar
Department of Infectious Disease, Faculty of Medicine, Imperial College London, UK
Metabolic control of regulatory T cell identity

Clarissa Campbell
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
T cell regulation by bacterial metabolites



01.04.2025
TBA
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06.05.2025
Linda Sinclair
School of Life Sciences, Cell Signalling and Immunology, University of Dundee, UK
TBA

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03.06.2025
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